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The FDA announced the approval of the new weight reduction drug on Sept. 11, 2014. The drug name is Contrave.

Using two separate drugs to lose weight naturally can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight-loss and the people who go through it you should err assisting caution and allow FDA do its job and demand some investigation be done in order that the public understands the side effects and dangers of the medications before we take them. Keep in mind that drug companies have been in business to earn money and that they would say anything to keep people on the medications.

Researchers found that participants investing in this drug for any year, lost excess weight within a month and have kept the body weight off through the 56 weeks from the study. Contrave can be a combination of the drugs naltrexone and bupropion, which usually reflect a fresh trend of weight-loss drugs that are made up of many active ingredient, which can make them more effective and safer.

Combo-pilling could be the newest fad or better yet the newest in the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is now popular may be the fact that since right now there aren't long term prescription diet pills that have been authorized by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be approved by the FDA.

Seizures are a side effect with Contrave and really should not be taken in individuals with seizure disorders. The drug also can raise blood pressure and pulse rate, and really should not be used in people with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure level and heartrate and must stop used in patients with uncontrolled high blood pressure, as well as by anyone with heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients having a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients on the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stop smoking.

Suboxone consists of two drugs; buprenorphine and naloxone. The naloxone is irrelevant if the addict uses the medication properly, but if your tablet is dissolved in water and injected the naloxone will result in instant withdrawal. When suboxone is used correctly, the naloxone is destroyed inside liver after that uptake from your intestines and it has no therapeutic effect. Buprenorphine is the active substance; it really is absorbed beneath the tongue (and throughout the mouth) but destroyed from the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I manipulate this formulation in the event the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I also have treated addicts who may have had gastric bypass, where the first area of the intestine is bypassed and the stomach contents empty in a more distal part of the small intestine. In such cases the naloxone escapes ?first pass metabolism', the method with normal anatomy in which the drug is taken up with the duodenum and transferred directly to the liver from the portal vein, where it really is quickly and completely destroyed. After gastric bypass naloxone can be taken up by servings of the intestine which aren't served from the portal system, causing blood amounts of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.

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